News
News from the Ghesquière lab
Check out our new publication with Mayo Clinic, on repurposing an existing drug for diabetes, to improve the lives of PMM2-congenital disorder of glycosylation (PMM2-CDG) patients. It was published in Cell Reports Medicine: Tracer metabolomics reveals the role of aldose reductase in glycosylation.
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Isabelle Adant, MD, succesfully defended her doctoral thesis on "Mapping and treating metabolic re-wiring in mitochondrial disease" (promotor: Prof. David Cassiman). Congratulations Dr Adant!
Bart Ghesquière gave a lecture during the NMC BeNeLux online seminar (24 Nov)
Julie De Beule, MD, succesfully defended her PhD thesis on "The road towards reducing preservation injury & predicting donor kidney viability". Congratulations Dr De Beule!
Our pioneering work on setting up dedicated Core Facility career tracks has been published in EMBO Reports!
Over the past two years, the Core Facility heads and our Human Resources department have collaborated on setting up Core Facility specific career tracks, which were implemented last January. We received a lot of international interest for pioneering this. You can read all about the Core Facility tracks in our paper ‘How tech-savvy employees make the difference in core facilities’ that was published in EMBO Reports.- Read more
The VIB Tracer Metabolomics Course (22 April) by Bart Ghesquière and Sam De Craemer was highly appreciated - nice to have such and interested and active audience.
The Metabolomics Expertise Center obtained FWO funding for Medium AND Large Scale Infrastructure! It was hard work but we're very proud!
Bart Ghesquière gave a lecture on "Theoretical Tracing of Carbons across the Metabolic Network" at the Applied Bioinformatics in Life Sciences conference in Leuven (10-11 March) - Read more
Bart Ghesquière gave a lecture at the 14th International Congress of Inborn Errors of Metabolism (Sydney, Australia)
Together with Prof Swinnen, Bart Ghesquière gave a seminar on "Mass Spectrometry Imaging", during the webinar “Opening the Future - Spatial Multiomics Platform” - Read more
MEC received a FWO Large Equipment grant for a new mass spectrometer - honoured and proud!
Congrats to Silvia Radenkovic on obtaining a long research FWO travel grant! Silvia will join Eva Morava's lab at Mayo Clinic to validate novel in vivo treatment strategies for the treatment of inborn errors of metabolism and build a strong international network
Dries Verdegem gave a hands-on bio-informatics course on MEC toolset for metabolomics
Bart Ghesquière gave a Seminar on "Tracer Metabolomics" at the VIB Medical Technology center, showing technological possibilities of the Metabolomics Expertise Center
Bart Ghesquière did the kick-off for the VIB training on metabolomics data interpretation in Leuven, together with Geert Goeminne.
Proud that our 'tracer-based diagnostic platform for anoxic kidney injury’ has been selected for the Fund for Translational Biomedical Research. For three years, the project will get an annual budget of 80keuro to study clinical applications of basic research findings.
How orbitrap helps VIB researchers expand the frontiers of science
Since its introduction in 2005, the Orbitrap mass spectrometer has quickly become a star in the research firmament. It has contributed to numerous significant breakthroughs in life sciences, especially in the fields of proteomics (the study of proteins and their functions) and metabolomics (the study of the intermediates and products of metabolism). First developed by the Russian physicist Alexander Makarov, a wide variety of Orbitrap mass spectrometers exist today, each with their own specifications. They all enable the quantification and profiling of small ionized particles using electrical fields. What makes Orbitrap such an important technology, and how does it help VIB researchers? We asked these questions to three researchers in separate VIB labs.
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